Cipro

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Cipro is a fluoroquinolone antibiotic. It is an antimicrobial agent for systemic use. The medicine inhibits the growth of pathogens that cause infectious diseases.

Indications

Cipro is used in the following cases:

  • infection of the middle ear (otitis media), sinuses (sinusitis, including sinusitis, frontal sinusitis, ethmoiditis, sphenoiditis, pansinusitis) caused by G-bacteria (gram-negative);
  • infection of the lower respiratory tract caused by Gr + bacteria (gram-negative) – chronic obstructive disease, pneumonia (except pneumococcal), cystic fibrosis, bronchiectasis (local bronchodilation);
  • kidney infection (pyelitis, pyelonephritis), urinary tract (urethritis, cystitis);
  • infection of soft tissues, skin caused by Gr + bacteria;
  • intra-abdominal (intra-abdominal) infections;
  • infection of bones, joints;
  • infection of the gastrointestinal tract (intestinal infections caused by enterotoxigenic strains of Escherichia coli, Campylobacter jejuni);
  • infection of the pelvic organs (adnexitis, prostatitis), including gonorrhea;
  • infection of y patients with reduced immunity (if neutropenia is detected).

Contraindications

Do not take Cipro with:

  • allergies to ciprofloxacin, other quinolones, excipients of this medication;
  • with the simultaneous use of tizanidine;
  • children;
  • pregnancy;
  • lactation.

Dosage and administration

  • Respiratory tract infection: 500-750 mg x2 times/day – 7-14 days;
  • Complicated pyelonephritis: 500-750 mg x2 times/day – at least 10 days, and in some cases (for example, with an abscess) – up to 21 days;
  • Urinary tract infection: uncomplicated cystitis – 250-500 mg x2 times/day – 3 days;
  • Complicated cystitis, uncomplicated pyelonephritis: 500 mg x2 times/day – 7 days;
  • Prostatitis: 500-750 mg x2 times/day – 2-4 weeks (with exacerbation), 4-6 weeks (with chronic course);
  • Genital infections: fungal urethritis, cervicitis – 500 mg once;
  • Orthoepididymitis, inflammatory processes of the pelvic organs: 500-750 mg x2 times/day – at least 14 days;
  • Intestinal infections, intra-abdominal infection: 500 mg x2 times/day – 1 day;
  • Diarrhea caused by Shigella dysenteriae type I – 500 mg x2 times/day – 5 days;
  • Diarrhea caused by Vibrio cholera – 500 mg x2 times/day – 3 days;
  • Typhoid fever – 500 mg x2 times/day – 7 days;
  • Intra-abdominal infection caused by Gr-microorganisms – 500-750 mg x2 times/day – 5-14 days;
  • Infection of soft tissues, skin: 500-750 mg x2 times/day – 7-14 days;
  • Infections of joints, bones: 500-750 mg x2 times/day – for a maximum of 3 months;
  • Аor prophylaxis/treatment of infections in patients with neutropenia: 500–750 mg x2 times/day – until neutropenia ceases;
  • For the prevention of invasive infection caused by Neisseria meningitides: 500 mg once;
  • For prevention after contact with the patient, as well as the treatment of anthrax: 500 mg x2 times/day – 60 days from the date of confirmation of infection.

Overdose

Overdose is manifested by headache, fatigue, confusion, dizziness, cramps, hallucinations, abdominal discomfort, the appearance of crystals, blood in the urine, impaired renal/liver function. As a first aid, it is recommended to lavage the stomach, take antacids.

Side effects

The following side effects of Cipro are possible:

  • loose stools;
  • nausea;
  • eosinophilia;
  • fungal superinfection;
  • lack of appetite;
  • agitation;
  • hyperactivity;
  • headaches;
  • taste disturbances;
  • dizziness;
  • sleep disorders;
  • vomiting;
  • flatulence;
  • pain in the stomach/intestines;
  • increased activity of liver enzymes;
  • itching;
  • increased bilirubin;
  • musculoskeletal pain;
  • rash;
  • urticaria;
  • impaired renal function;
  • fever;
  • fatigue;
  • changes in white blood cell count;
  • anemia;
  • inflammation of the colon;
  • decreased numbers platelets;
  • increased sugar levels;
  • depression with the appearance of suicidal thoughts;
  • pathological dreams;
  • changes in sensitivity;
  • decreased blood pressure;
  • hearing disorders;
  • tachycardia;
  • fainting;
  • impaired liver function;
  • choking;
  • jaundice;
  • hepatitis;
  • muscle pain;
  • photosensitivity;
  • joint inflammation;
  • muscle cramps;
  • increased muscle tone;
  • kidney failure;
  • anaphylactic shock;
  • migraine;
  • mental reactions with suicidal attempts;
  • unstable gait;
  • impaired coordination;
  • odor perception disorder;
  • color perception changes;
  • vasculitis;
  • increased intracranial pressure;
  • pancreatitis;
  • petechiae;
  • erythema;
  • liver necrosis;
  • syndrome Stevens-Johnson;
  • muscle weakness;
  • toxic epidermal necrolysis;
  • inflammation/rupture of tendons (often Achilles);
  • increased sweating;
  • swelling;
  • increased prothrombin time;
  • periphery eskaya neuropathy;
  • arrhythmia;
  • ventricular tachycardia;
  • pustular rash.